1933 – First human-to-human kidney transplant
1954 – First successful kidney transplant
1966 – First simultaneous kidney/pancreas transplant
1967 – First successful liver transplant
1968 – First successful isolated pancreas transplant; first successful heart transplant; Donor Card created under the Uniform Anatomical Gift Act
1981 – First successful heart-lung transplant
1983 – First successful single-lung transplant; Cyclosporine, the first organ-rejection suppressant, was introduced
1984 – The National Organ Transplant Act passed, thereby establishing a national system for organ transplantation and prohibiting the sale of human organs
1986 – First successful double-lung transplant; UNOS received federal contract to oversee the national transplant network 1987 – First successful intestinal transplant
1988 – First split-liver transplant
1989 – First successful living-donor liver transplant
1990 – First successful living-donor lung transplant
1992 – UNOS helps found the Coalition on Donation, now known as Donate Life America
1998 – First successful living-donor liver transplant between adults
2000 – The Organ Procurement and Transplantation Network (OPTN) becomes federally regulated by the U.S. Department of Health and Human Services
2001 – First time the yearly number of living organ donors exceeded the number of deceased organ donors
2003 - First tongue transplant takes place; the recipient could not move the tongue on its own or taste, but he was soon able to swallow liquid
2005 - Surgeons in France perform first ever face transplant
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